Sentence examples for To cetp from inspiring English sources

In particular, we see that the model can describe the dynamics of HDL-C rise due to CETP inhibition, as well as a drop in LDL-C due primarily to the decreased CETP mediated CE flux from HDL to VLDL and LDL.

Compounds that could grab on to CETP, thereby blocking its function, were also greasy and didn't dissolve well in the blood.

Using 1,156 fewer samples we still reproduced the genome-wide significant association to CETP (rs3764261, p = 2.63e-13), and a highly significant association to both LPL (rs1441762, p = 1.53e-6 1.53e-6PC (rs11856159, p = 1.59e-6).

Elevated HDL secondary to CETP deficiency may not then be entirely atheroprotective.

Ultimately, we performed docking experiments to characterize the putative molecular binding mode for leoligin to CETP.

Therefore, we searched for new drugs that bind to CETP and modulate its activity.

So Pfizer scientists began a search for a drug to lower CETP levels research that led to torcetrapib.

Leoligin seems to differ from probucol, as leoligin did not to increase CETP mass in CETP transgenic mice, whereas probucol increases both human CETP plasma levels and CETP activity [12,14].

The researchers also independently connected the disease to ABCA1, CETP, and LPL when they scanned the genomes of 2157 people with macular degeneration and 1150 controls.

Evacetrapib exposure increased in a less than dose-proportional manner, similar to other CETP inhibitors.

The worrying finding that CVD incidence was related inversely to plasma CETP has since been reproduced in each of five further prospective cohort studies.