In particular, theoretical and empirical economic studies take into account only to a restricted extent the possibility that workers with similar productive characteristics receive different salaries.
Additionally, the effect depended only to a restricted extent on the drug, but more clearly on the cell line used (eg, NT2/paclitaxel: 1.2-fold increase with an IC50 in normoxia: 3.1 n M, and hypoxia: 3.7 n M; Figure 2A, and NCCIT/paclitaxel: >100-fold increase with an IC50 in normoxia: 4.3 n M, and hypoxia: 87 μ M; Figure 2B).
At least 3 factors were identified which acted to augment the fraction of early-eluting tumour glycopeptides: (a) increase of neuraminidase-sensitive sialic acid, (b) increase of neuraminidase-insensitive sialic acid that was sensitive to mild HCl hydrolysis, and (c) presence of sugar sulphate groups contributing to a restricted extent, relative to possible unknown factor(s).
What is more, it is particularly unclear how the new capital requirement will be met by Nationwide without to an extent restricting the supply of new mortgages or at least pushing up the cost of mortgages - because, unlike Barclays, it is a mutual with few obviously spare assets to sell and no access to the stock market for capital.
Technical possibilities of these modification methods, however, are, to a large extent, restricted by peculiarities of a vitreous state with characteristic effects of natural physical aging, functional non-reproducibility, and thermodynamic instability in view of high affinity to chemical reactivity.
The Republican Party today has been so completely taken over by its socially conservative wing, that to a large extent, restricting women's rights is no longer a fringe view in the party, but is the core message, along with being against taxes and hating President Obama, of the party.
The surrogate outcome measures developed to date are restricted, to an extent, by the common data items available from all cancer registries.
Therefore, the rapid development of Chinese modern service industry has been restricted to a particular extent, for example, the logistics and financial industries' ability to promote growth in real economy has been restricted.
Together, they represent a small subset of the known scaffolds for hinge/ATP site binders [36], which are already a restricted set [37] compared to proposed extents of possible scaffold diversity [38].
For the European Union, it is clear that any external attempts to influence the activities of EU natural or legal persons is unacceptable, and its legislative moves are an attempt to restrict the extent of such activity.
Under certain conditions, however, groundwater contamination remains restricted to a tolerable extent because of natural attenuation processes.
