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Time discontinuation service became the rule.
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Appropriately timed discontinuation of chemotherapy is essential for the patient's quality of life.
Similarly, we found that infliximab use was associated with the longest median time to discontinuation and lowest discontinuation rate and that adalimumab was associated with the highest discontinuation rate and shortest time to discontinuation among first-line anti-TNF therapies.
Of the 35 subjects who had discontinued AI treatment, median time since discontinuation (IQR) was 10.2 months (31).
The proportion of patients discontinuing therapy and the time to discontinuation were determined for the anti-TNF and abatacept cohorts.
Kaplan Meier (KM) plots were created for both time to discontinuation due to treatment failure and time to any discontinuation.
Additional descriptive statistics were compiled for both time to discontinuation due to treatment failure and time to any discontinuation.
Time to discontinuation due to treatment failure and time to any discontinuation were compiled starting from the first extension study dose.
Patients who discontinued treatment were censored at the time of discontinuation.
There was a statistically significant overall difference among all treatment groups in time to discontinuation for any reason (p < .001) and time to discontinuation due to lack of efficacy (p < .001) (data not shown).
Therefore, in addition to examining the laboratory values most proximal to the time of discontinuation, we also examined the changes in lab values leading up to discontinuation.
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