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They perform their biological function coherently by tightly connection across biomolecular levels.
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Geomorphic systems consist of coupled subsystems with traits of small-world networks (SWN), characterized by tightly connected clusters of components, with fewer connections between the clusters.
In contrast to the specificity of the networks for the darkgrey and lightgreen modules, the EnrichmentMap for the probe-based analysis gene set shown in Additional file 2: Figure S4 is less tightly connected with many nodes having zero connections.
They may also be so tightly connected that they can reflexively anticipate their teammates' moves and reactions, they can "finish each other's sentences". To be such high performing teams they need this level of close connection.
These types of regulatory linkages are unlikely to be restricted to Drosophila, thus the picture that emerges of RB pathways is one of tightly interwoven connections, where transcriptional links mediated through this family of proteins are likely to play important roles in adjusting the set points of numerous signaling pathways.
According to our experience, this problem could be significantly minimized by tightly sealing the connection between the microfilter and capillary and a carefully operation.
Then came a still photo of their hands tightly clasped, emphasising the connection between the two men.
Solder the two wires at one end of the horizontal piece together and repeat for the other end (if not soldering, create a solid electro-mechanical connection by tightly twisting the wires together instead of soldering).
A protein complex is decomposed and pruned into several small subnets connected tightly by extended k-cores and the proteins in the complex of loose connections that are abandoned.
Vangone and Bonvin found that the number of connections between each pair of proteins was a strong predictor of how tightly the proteins connect to each other.
It's very important that all connections are tightly sealed and fit well.
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