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GSEA asks whether the genes that make up a particular gene set are randomly distributed throughout the ranked list of genes, or whether they have a tendency to cluster at the top or bottom of the list.
Therefore, the null hypothesis of a GSEA is that the distribution of a gene set throughout the ranked list of genes is random with regards to the two treatment conditions being compared.
The pairwise correlation between Hap4 and its targets varies, and since CLR scores all interactions individually, they are dispersed throughout the ranked list of interactions.
When calculating the significance of a gene set, the null hypothesis is that the genes in a set are randomly distributed throughout the ranked list of genes from the microarray experiment.
Typically each male has zero or multiple matings to make, and there is a ranking for each mating, rather than for each male, such that matings for a given male are generally dispersed throughout the ranked list.
Given an a priori defined set of genes S (sharing the same GO category), the goal of GSEA was to determine whether the members of S were randomly distributed throughout the ranked list or primarily found at the top or bottom.
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Indeed quietness appears not to have been a determining factor throughout the ranking.
Many employees throughout the agency ranked poor radio performance as their top safety issue.
Cognizant also drives accountability for talent throughout the management ranks, since the executive team cannot be the only ones focused on this issue.
The study found that high-speed Internet access throughout the house ranks as the most popular reason for structured wiring, followed by monitored security systems, and then the ability to play music from one stereo system in several rooms.
The commission also reported a "willful blindness" to corruption throughout the ranks of the NYPD.
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