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This trial represents the first effort to test the efficacy of a targeted therapy in a molecular defined subset of KRAS mutant NSCLC and may serve as a model for future trials.
This trial represents the first clinical application of the GVAX/anti-CTLA4 combination.
This trial represents the farthest advance of any TB vaccine candidate in clinical testing since the introduction of BCG vaccine in the 1930s.
This trial represents the first attempt to assess the effectiveness and cost-effectiveness of an Internet-based weight control package against usual care for the management of obesity.
This trial represents a pan-Canadian partnership of sites and investigators/surgeons and is the first randomized trial of the pan-Canadian Network for Oral Cancer Control or PanCanNOC.
This trial represents a relatively unusual example of a large multi-centre randomised controlled trial designed to provide rigorous evidence about the costs and benefits of a new approach to service delivery.
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Thus far, 2,500 patients in the USA have been enrolled in one of the 24 arms of this trial, representing one-half of the recruitment goal.
"Withdrawal of funding at this late stage has made it impossible to substitute any insurance-based funding in the time available … This trial represent the only opportunity for these children by proving causation of injury to establish a basis of entitlement to compensation for their injuries".
This trial represented a very important step in this field, because it was specifically designed for elderly patients.
This trial represented a pilot study that was designed to demonstrate the feasibility, acceptability, and efficacy of the intervention; therefore, a power analysis was not conducted.
The results of this trial represent the data of the 262 European participants of the REVERSE-trial with 180 patients in the verum-group with enabled CRT function compared to 82 patients with disabled device function.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com