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This issue is evident in our study, where despite identifying increased mRNA levels for two NF-κB target genes, the NF-κB luciferase reporter assay shows decreased expression of the reporter gene in cells treated with doxorubicin (Figure S2).
This issue is evident in many areas of care.
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Zimbabwe was among the first of many countries to answer the call, but its commitment on this issue was evident long before that.
This issue was evident during the piloting of various models at the concept evaluation stage [ 1].
Another key area was the efficient transfer of both verbal and written information, and this issue was evident even prior to the birth itself.
This issue was evident in our EPS2 pre-implementation study of pharmacy work practice as pharmacists showed signs of not using EPS2 Smartcards as intended.
This issue was evident during the GP fund holding and total purchasing pilot (TPP) periods where the average size of the commissioning consortia was small and purchasing decisions were divided between several local commissioning organisations.
The need for greater understanding of this issue was evident in calls to "look into alternative approaches" (#9 SE Asia), and "Study [the] income generation potential of different employment support mechanisms to allow customised regional plans" (#17 South Asia).
The magnitude of that issue is evident in every Chinese city.
The animosity around the issue is evident in a tweet by Senator Roberto Formigoni, a political heavyweight and ultra-religious conservative, who used language unimaginable in public discourse in many other countries: the "smell of loss on the #Cirinnà bill is causing gays, lesbians, bi-transexuals and assorted faggots to break into hysterics," he tweeted.
The sensitivities surrounding the issue were evident this week when a spokeswoman for Gov. Bill Richardson of New Mexico, who is seeking the Democratic presidential nomination, said Mr. Richardson would not participate in the debate, which is scheduled for September.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com