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These testes exhibited looser structure with fewer seminiferous tubes, spermatogonia, and spermatozoa than in controls.
These testes contained spermatogonia A, spermatogonia B, and spermatocytes but no spermatozoa.
These testes contained male germ cells (spermatogonia A, and both spermatogonia A and B in more advanced fish) but were connected to the body wall by two distinct points of attachment forming a "female-like" duct or ovarian cavity.
These testes contained male germ cells (spermatogonia A, and both spermatogonia A and B in more advanced fish) but were connected to the body wall by two distinct points of attachment, forming a femalelike duct or ovarian cavity.
If left in this position until adulthood, these testes will deteriorate to the Sertoli-cell-only state, leading to infertility in 100%.
Marker analyses of these testes (n = 8) revealed no abnormalities when compared to controls (here, Map3k1ΔKD/ΔKD embryos).
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Frequently in these animals the testes are drawn back into the body cavity except in the breeding season, when they again descend and mature; this process is known as recrudescence.
We hypothesize that a crucial link that can explain this phenomenon is the lack of expression of the DAZ gene in the testes these cases.
Treatment with cisplatin resulted in a marked decrease in the expression of nephrin and podocin and induced a shift of both proteins from linear to granular expression patterns, accompanying the increased apoptotic index in the testes; these changes were partially restored by the additional administration of candesartan.
As they bump, grind and thoroughly enjoy themselves among their adoring crowd ("Ladies from the easties and from the westies / Trying to molest these beautiful testes"), no one will mistake them for failures.
VASA expression was examined in these monkey testes by immunohistological staining.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com