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In lower respiratory tract infections there are several trials that clearly demonstrated that antibiotic therapy can be guided by PCT measurements [ 25- 27].
There are several trials studied on the effects of route of fluid administration on CI-AKI prophylaxis.
There are several trials that effective immune-based anti-tumor therapy has been tried with cytokines, passive and active immunotherapeutic methods, such as INF-α, antibodies, dendritic cells, and T cells, including tumor antigens [ 18- 20].
There are several trials that have used behavioral interventions with similarities to CB principles as well as studies that have integrated CB principles with other forms of rehabilitation in OA patients.
Although there are several trials with a RAS based pharmacotherapy that report a reduction in the development of diabetes compared to diuretics and betablockers, these analyses were mostly post-hoc and not predefined.
Currently, 1 RM tests are not validated for elastic resistance training, because most of the available devices do not have a determined load scale for exercises, and, although there are several trials to determine elastic force, none of them developed a valid and reliable method for elastic tubes and bands for scientific and professional use [ 44].
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Among the CENTRAL trials, I found no reports of adverse treatment outcomes from acupuncture in Japan or the U.S., whereas there were several trials of herbal medicine in the U.S. where unforeseen difficulties developed.
There have been several trials investigating the efficacy of different drugs for PPMS without positive results.
There have been several trials of IVIg in ITP since its first use in the mid-1980s.
There have been several trials in which high doses of vitamin D were administered without any adverse events.
Given the potential role of bacterial infection in ATH, there have been several trials of antibiotic treatment, but without significant benefit [ 201, 213, 214].
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