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When a better hypothesis is found, it's added to the set, while the worst hypothesis in the set is removed.
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After you ride the subway, without getting stuck, you successfully disprove your worst hypothesis.
Taking the worst-case hypothesis (i.e. high survival in the control arm = 25%) and in order to obtain 80% power with a two-side alpha level of 5%, with a follow-up period of 2 years, 138 patients are required per arm.
The "worst is over" hypothesis is a powerful strategy, but timing needs to be near perfect.
The experiment used an autobiographical memory retrieval task during script-driven imagery to investigate the hypothesis that the worst moments of trauma memories in PTSD are disjointed from other autobiographical material.
Wilcoxon matched pairs sign rank sign test = 5, P = 0.004 As a complement of the above result, Table 3 and Figure 4 (top right) test the worst outcome of the working hypothesis: the matching of behavioral choice in Questionnaire 3.b with the worst rated items.
At worst, the hypothesis driving the analyses was "irresponsible," a scientific adviser to the commission wrote.
However, even that, more logically consistent and less outrageous hypothesis would be the worst kind of adaptationist just so story.
The worst?
The worst of the worst".
At the worst times.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com