Exact(53)
The substitutions of Arg at both positions 11 and 20 by His were also conserved.
The substitutions of residues S78, H86 and Q113 only mildly affect RNA binding and catalysis, so they are not essential for CMTr2 MTase activity.
The substitutions of alkyl group and alkyl-polymer fluorene precursors were helpful for the red shift of emission wavelength of as-formed polyfluorenes.
The substitutions of S76 with a branched hydrophobic residue or of S72 with a bulky Tyrosine, impacts the inward-facing conformation in which there is close juxtaposition of TM2 and TM11.
The substitutions of E2 and K14 also altered the general properties of AChE586-599, such as its net charge and isoelectric point (pI).
The substitutions of crucial Lys into Met in the nucleotide binding domains (NBD) carried by MM (position 939 and 1952) are known to lead to a complete loss of function of the ABCA1 transporter without affecting its trafficking.
Similar(7)
"Automation is fundamentally the substitution of capital for labour.
It may even mean the substitution of lower grade ingredients.
"I don't understand the substitution of Lavezzi.
The substitution of the first for the third person in conversation is managerial usage.
Another change was the substitution of the man-and-canoe pictograph for the arrowhead projection.
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