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Given the substantial obstacles, will the N.I.H. project, which has not even really begun, be worth the immense expense and effort?
But even if Spanish opposition melts away before Sunday, the bitterness over Gibraltar, over fishing rights, over ensuring that the UK has no competitive advantages over European businesses in a post-Brexit trade deal, these are examples of the substantial obstacles the UK will face from EU countries in negotiating a trade deal with EU after Brexit.
Punishment of these criminals is more likely to be achieved through courts-martial because of the substantial obstacles facing civilian prosecutions of criminals in conflict zones.
Should he overcome the substantial obstacles involved in physically selling the gold, Gaddafi should be able to fund his forces for some time.
Despite the substantial obstacles to ARV adherence, motivation to adhere was extremely high in our study, consistent with previous studies.
However, these policies must take account of the substantial obstacles to change imposed by obsolete structures, institutions, and beliefs [ 30, 31].
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Evidence from PeriPeri U's 2015 summary evaluation report underlines that this represents one of the most substantial obstacles to advancing the field (Ofir and Mentz 2015).
The Trump administration is renewing an effort to replace US troops in Syria with an Arab force, but the proposal faces substantial obstacles and could potentially exacerbate the conflict.
The introduced SGO particles serving as fillers in the SA polymer create substantial obstacles to the linked hydrophilic passages.
At this point, I'll just state that although I agree completely with the Reviewers that there are substantial obstacles to the introduction of the Scans into clinical practice, I also feel that the obstacles are definitely surmountable, and that the time to begin working on these problems is now.
Thirty-six states have constitutional barriers similar to Washington's to supporting religious institutions with public money, and these have proved to be substantial obstacles to the spread of the school-choice movement.
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