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The PUM concept gives the possibility to increase cell dimensions without reducing the output.
The PUM model could explain the behavior of the M ≥ 7. 3 earthquakes that have occurred during the past 500 years, as shown in Figs. 5 and 6, and Table 2.
The PUM model could explain the behavior of many of the M ≥ 7.0 earthquakes (particularly M ≥ 7. 3 earthquakes) that have occurred during the past 500 years, as shown in Fig. 3(a).
The PUM model proposes that the accumulated stress inside the old plate is released from the bottom to the top in turn, and this process is repeated periodically without a long period of quiescence.
The pum locus spans over 160 kb, so four separate products were sequenced that include most of the exons.
Therefore, the PUM model for M0 = 7.0 is not significant.
Similar(18)
Moreover, the sequence preceding the PUM-HD motif of PUM2 is also important for this interaction.
In previous study, the PUM-HD motif of PUM2 is responsible for the well-known role as translational repressor [14].
Three putative domains including the S motif (serine rich regions), the Q/A motif (glutamine/alanine-rich regions) and the PUM-HD motif (RNA-binding domain), are present in PUM2 [13].
The PUM-HDs of mammalian PUM proteins are highly related (91% amino acid identity) and all of the critical amino-acids that make direct contact with the RNA are fully-conserved [11].
However, our results showed that the N-terminal fragment (aa 1 742) which lacked the PUM-HD motif still could bind to Aurora-A and another motif, the S motif, is responsible for this interaction.
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