Sentence examples for The major loop from inspiring English sources

The major loop relies on two transcription factors, CLOCK and BMAL1, forming a complex that stimulates the expression of target genes by binding to regions of DNA called Enhancer-boxes (E-boxes) thareassociatedated with the target genes.

Step1 Enter the major loop and repeat until the defined maximum number of iterations is exceeded.

ϕ k is the minimization variable in the major loop, it is the phase vector in this problem.

d k is a search direction in the major loop while is the search direction in the QP loop.

k is used as an iteration counter in the major loop and l is the counter in the QP loop.

Microtubule-stabilizing agents use a common mechanism to structure and stabilize the major loop in tubulin that controls microtubule dynamics.

The residues where mutation does not provoke a phenotypic response (in yellow) are not located in the active site or any of the major loops known to play a role in Kinesin-1 motion.

By simple comparison of the sequence specific assignment of WTVP6 on the H-N-HSQC spectrum shown in Fig. 1A, many of the signals could be assigned unambiguously for the short deletion construct (d1VP6, data not shown), demonstrating that the lack of this major loop did not affect the structure of core domain, even when the entire loop was removed (d2VP6, data not shown).

To test the hypothesis that multiple GSMs act by allosterically influencing PS1 conformation, and to directly monitor PS1 conformation in live cells, we developed a new assay that monitors proximity between the PS1 NT and the major cytosolic loop between PS1 transmembrane domains 6 and 7 (TM6-7 loop).

The SQP implementation consists of two loops: the phase solution is updated at each fiiteration in major loop with k as the counter, while itself contains an inner QP loop to solve for optimum search direction d k.

While this forms the major feedback loop of the mammalian molecular clock, the overall mechanism also depends on additional feedback loops driven by ROR and REV-ERBα/β (Preitner et al., 2002; Sato et al., 2004; Ueda et al., 2005; Cho et al., 2012).