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The major difficulty is that Jan's masterpiece, The Adoration of the Mystic Lamb altarpiece, has a wholly questionable inscription that introduces Hubert van Eyck as its principal master.
The major difficulty of the Poisson Neumann problem solvability is addressed and correctly treated.
The major difficulty stems from the network model which consists of highly nonlinear coupled equations.
The major difficulty is to calculate the ultimate stress in unbonded tendons.
The major difficulty of such design problems lies in modeling the diversity of daily travel demands.
The major difficulty for using shadow information is due to the complicated lighting conditions in indoor environments.
The major difficulty in using the LRT is its requirements on the exact distributions given in (5).
The major difficulty in moving this approach to TEM is designing an aperture to block electrons rather than photons.
The major difficulty is that a closed form solution to governing equation of motion is not obtainable.
The major difficulty lies in the realistic estimation of the dynamic forces arising out of complex flow pattern.
The major difficulty lies in the development of models which are both physically motivated and sufficiently mathematically well defined to be used in finite element applications.
More suggestions(15)
The major disadvantage
The serious difficulty
The principal difficulty
The major constraint
The severe difficulty
The major predicament
The fundamental difficulty
The tremendous difficulty
The enormous difficulty
The substantial difficulty
The major inconvenience
The main difficulty
The major trouble
The considerable difficulty
The major dilemma
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com