Sentence examples for The largest challenges from inspiring English sources

The largest challenges appear to be overcoming the cellular immune responses to the AAV capsid; preexisting AAV neutralizing antibodies, which immediately exclude approximately 50% of the target population; and the ability to scale-up vector manufacturing for widespread applicability.

The largest challenges were encountered during model selection.

One of the largest challenges the team face is that Wikipedia is primarily text-based.

Another of the largest challenges facing youth sports: finding qualified coaches.

Because his vision is so expansive, he can take on the largest challenges, rather than small, narrowly defined ones.

According to these trends, increasing test data volume is one of the largest challenges in the testing industry.

It was the largest challenge to the regime since the 1979 revolution.

The ability to strain out extraneous light input is the largest challenging still facing the Leap.

The police says that security around the Olympics is the largest challenge they have faced.

For park advocates, however, the open ocean — far from any landmass — remains the largest challenge.

"The largest challenge has been integrating storyline with the procedural mechanics," says van der Werf.