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We investigated maternal (n = 224) and cord blood (n = 293) from mother-newborn pairs that were enrolled in the ENVIR ONAGE birth cohort.
In the framework of the ENVIR ONAGE birth cohort (ENVIRonmental influence ON early AGEing), we hypothesized that mitochondrial oxidative DNA damage, as exemplified by mitochondrial 8-OHdG, is associated with airborne PM exposure during gestation.
Expression of 10 target genes in the brain-derived neurotrophic factor (BDNF) signaling pathway were quantified in placental tissue of 90 mother infant pairs from the ENVIR ONAGE birth cohort using quantitative real-time polymerase chain reaction.
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The ongoing ENVIR ONAGE birth cohort enrolls mothers giving birth in the East-Limburg Hospital (ZOL; Genk, Belgium).
In this case, the only parameter needed to be changed is the environmental variable (envir).
The current study is part of a new initiated and ongoing birth cohort "ENVIR ONAGE" (the acronym emphasizes the environmental influence on the aging process).
To support findings from spaceflight that the supplementation of LB media with selected M9 salts disrupts S. typhimurium responses to this envir onment, cultures containing LB media, M9 media, and LB-M9 salts media were grown in the RWV at low shear modeled microgravity (LSMMG/spaceflight analogue culture conditions) and control orientations (Figure S1) and evaluated for changes in acid tolerance.
We recruited mother-newborn pairs (only singletons) in the East-Limburg Hospital in Genk, Belgium who are part of the ongoing birth cohort "ENVIR ONAGE".
Table 3 Source separation results in an anechoic enclosure (cf. Figure 1 ) with background noise White noise Babble noise Factory noise Envir.
Table 4 Source separation results in a reverberant enclosure (cf. Figure 1 ) with background noise White noise Babble noise Factory noise Envir.
Table 9 Function of analysis Function of analysis Conceptual studies Empirical studies Formal models Total SCM 6 16 12 34 Sourcing 3 8 8 19 Envir./CSR mgmt 1 5 – 6 Logistics – 3 7 10 Network design – – 6 6 Production – 3 1 4 Other – 6a 5b 11 Total 10 41 39 90 a Materials management (1 paper), product development (3), standards/certifications (2) bPricing (2 papers), technology/IT (3).
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