Exact(1)
In the DECL phase, HSP70_1 and HSP70_4 were 3-fold up-regulated (p < 0.001), while HSP90 expression levels increased by 4-fold (p < 0.001).
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Interestingly, a decrease in expression levels was time-dependent in Si-starvation conditions only for GSH-S, GR, GPX and GST, with highest expression in the exponential phase (EXP) and lowest in the declining phase (DECL).
At the gene level, HSP expression levels increased in the stationary (STAT) and decline (DECL) phases of the growth curves in each studied condition (see Figure 1).
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where decI refers to the interval data in deciles 2 to 9, decR refers to the right-censored data in decile 10, and decL refers to the left-censored data in the first decile.
ABC also increased in STAT and DECL in the complete medium curve (p < 0.05; Figure 1a).
GR also was significantly up-regulated in DECL of the CO2-Si growth curve (p < 0.001; Figure 1c).
The current study involves the development of a representative RELAP5/SCDASIM model for AP1000 based on publically available data and its verification for a double ended cold leg (DECL) break in one of the cold legs in the loop containing core makeup tanks (CMT).
Expression levels of heat shock proteins, aldehyde dehydrogenases, glutathione-related enzymes and other antioxidants in S. marinoi during stationary (STAT; green bars) and declining (DECL; red bars) growth phases in the CO2-enriched condition, using the exponential phase as control (x-axis; * for p < 0.05, ** for p < 0.01 and *** for p < 0.001).
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