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India's problem generating enough power has been one of the biggest handicaps to its prospects for sustaining rapid economic growth, analysts say.
Other innovators are also exploring the possibilities of renewable energy, as one of the biggest handicaps for traditional desalination is its huge consumption of fossil fuels.
The 2-0 score flattered the home side, and it is no exaggeration to say that the foul weather and the cloying heat were the biggest handicaps for France to overcome.
Yet the tax may eventually not only bring new fiscal stability, but also reduce the burden of cascading excise and sales taxes that is one of the biggest handicaps facing manufacturers.
"That's one of the biggest handicaps for hip-hop, the idea that it doesn't incorporate different styles.
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Brazil already spends a higher share of GDP on schooling than most OECD countries.Bad teachers are the biggest handicap.
It has long been noted here that space is the biggest handicap to the widespread use of personal computer.
In fact, he doesn't go for big, named threats, doom-calling, dread-provoking, but two things trouble him: "The biggest handicap that conservation faces is that we humans still consider ourselves to be separate from the rest of life, and the rest of life is merely there to support us.
For more mature collectors, of any age, the focus has shifted from accumulating stamps to studying history, especially history illustrated by the passage of a letter from point A to point B. The biggest handicap that new collectors face is that many fewer people use stamps on their mail these days, and when they do, the stamps may not be worth collecting.
For more mature collectors the focus has shifted from accumulating stamps to studying history, especially as illustrated by the passage of a letter from point A to point B. The biggest handicap new collectors face is that fewer people use stamps on mail these days, and when they do, the stamps may not be worth collecting.
"Fear of the unknown is the biggest handicap.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com