Sentence examples for That unf from inspiring English sources

However, the extensive data showing that PNR, the vertebrate ortholog of unf, functions both as an activator and repressor supports the hypothesis that UNF also acts as both a transcriptional activator and repressor of target genes (Chen et al. 2004, 2005; Haider et al. 2009).

Recently, an in vitro study suggested that UNF is a heme binding protein [48].

The observations suggest that unf is mainly involved in the formation of the adult MBs.

Taken together, these observations suggest that unf acts cell-autonomously to regulate individual axons' pathfinding (Fig. 7K,L).

However, its enrichment in the MBs strongly supports our observations that unf controls some MB-characteristic aspects of neural development.

Further analysis revealed that unf was required for proper axonal guidance of all three major types of the MB neurons.

The defects observed demonstrate that unf-interacting genes regulate MB development in a branch-specific manner.

These results demonstrate that the unf knockdown phenotype in α/β neurons was not due to the defects in α'/β' lobes.

Besides recapitulating the known MB phenotypes for three NRs, we found that unfulfilled (unf), an ortholog of human photoreceptor specific nuclear receptor (PNR), regulates axonal morphogenesis and neuronal subtype identity.

We found that most unf knockdown MBs (88%, n = 75) were grossly normal at mid-3rd instar larval stage when the MB primarily consists of γ neurons (Fig. 3A,B), although 12% of unf knockdown MBs had thinner dorsal lobes (n = 75; inset in Fig. 3B).

These observations reveal that 1) unf is largely dispensable for the initial larval-specific axonal morphogenesis of the γ neurons, but absolutely essential for the extension of the adult-specific γ axons during remodeling; 2) unf is necessary for the de-novo formation of α'/β' and α/β lobes.