Exact(17)
Finally, tissue-specific brain volume measurements showed that RIS subjects may have, similarly to RRMS patients, a significant amount of cortical atrophy.
We found that Ris reduced the downregulation due to DEX in a dose dependent manner.
In this study, we did not demonstrate that RIS applies to other insular populations/species.
We found that Ris prevents osteocyte apoptosis in GC-treated rats, according to previous findings by Plotkin et al. [ 12].
As already mentioned, we found that Ris treatment prolongs osteocyte lifespan, reducing their apoptosis induced by GC.
On the proximate level, we hypothesized that RIS is caused by increased activity levels in melanocortin receptors.
Similar(43)
The histomorphometric and BMD results of the contralateral tibias and lumbar vertebrae indicated that RIS-HA composite coating could induce bone mass augmentation and BMD increment significantly in non-peri-implant region, especially lumbar vertebrae.
We expected that higher RIS would be correlated with an increased likelihood of deciding to take medication.
A multivariate logistic regression analysis showed that 13/19 RIS had ≥70% probability of being classified as RRMS on the basis of their brain volume and lesional-MTr values.
We showed that the RIS is linked to increased activity of melanocortin receptors in our insular study population.
Recently, it has been reported that, although RIS had a role in mineralization, it did not change bone mass and bone structure markedly [ 8- 10].
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