Sentence examples for That nrf from inspiring English sources

Finally it should be noted that NRF is specific of IgG4 as none of the other IgG subclasses were found to show such activity (unpublished data).

This homeostatic function of SKN-1 in lipid metabolism suggests that Nrf proteins have a similar role in preventing NASH.

The fact that NRF has also been highlighted as the biggest research funding agency in Africa in the area of natural and physical sciences corroborates our data [ 11].

Although it is known that NRF-1 controls these dual pathways (glucose transport and oxidative phosphorylation), the actual molecular mechanisms involved surrounding this regulation remains elusive.

A possible explanation is that NRF-1 and mtTFA, which localize to mitochondria, are also substrates of SIRT3 and their activities are regulated by SIRT3.

Taken together our data strongly indicate that Nrf-2 dysfunction is present in CF epithelia and that, coupled with increased H2O2 production by SOD2, this results in the accumulation of H2O2.

Since CF epithelial cells exhibit significantly lower expression and transcriptional activity of Nrf-2, as demonstrated by a recent study [47], it is unlikely that Nrf-2/ARE is responsible for the increased basal expression of Prdx6 mRNA in Cftr−/− cells.

Moreover, recent studies demonstrated that NRF-1 regulates the expression of TFB1M [ 31].

These results suggest that NRF-2α physically binds the SIRT3 promoter to affect SIRT3 gene expression.

We found that nrf-5 and nrf-6 mutants (pale egg) were long-lived and that nrf-1, nrf-2, nrf-3, and nrf-4 mutants (Nrf but not pale egg) had wild-type or shortened lifespan (Table S2).

Although our mutagenic analysis was not exhaustive, our data suggests that NRF-1 and YY1 are both important positive regulators in the expression of HP1α.