It is likely that, FRF may also mediate its insulin secretogogue function through GLP-1 action as, flavonoids are known to increase GLP-1 level as well as inhibit dipeptidyl peptidase IV (DPP-IV), the enzyme that metabolizes GLP-1, both of which can efficiently up regulate insulin secretion from pancreatic islets in presence of glucose [ 31, 32].
Based on Eq. (68), it is straightforward to see that FRF matrix can be given by {mathbf{H}} omega ) = [ - omega^{2} {mathbf{M}} + iomega {mathbf{C}} + {mathbf{K}}]_{M times M}^{ - 1} [iomega {mathbf{C}}_{f} + {mathbf{K}}_{f} ]_{M times N}.
These results suggest that Sa-FRF and Sb-FRF demonstrated healing of the lesions induced by acetic acid.> -wrap-foot> ANOVA followed by Dunnett's test.* p < 0.05, ** p < 0.01.
These results suggest that Sa-FRF and Sb-FRF protect the gastric mucosa from ischemia/reperfusion-related injuries.> -wrap-foot> ANOVA followed by Dunnett's test.* p < 0.05, ** p < 0.01.
Figure 5 With vs. without piezoelectric transducer FRFs for H 12, Model 1 and Model 3 – Case Study 1. Figure 6 With vs. without piezoelectric transducer FRFs for H 13, Model 1 and Model 3 – Case Study 1. Regarding the signal measured by accelerometer, it is important to observe that the FRF curves are much clearer below 500 Hz.
It would appear from the present observations that, our FRF has potent ability to function as a potentiating insulinotropic agent for stimulating cAMP and Ca++ mediated insulin secretion under the permissive influence of glucose.
The experimental results showed that the FRF-based damage detection method could satisfactorily locate and quantify damage.
The results suggest that the Sa-FRF and Sb-FRF display gastroprotective activity at the dose evaluated.
The results show that the Sa-FRF (42 ± 1,6*), Sb-FRF (49 ± 4,3*), and cimetidine (22 ± 2,5**) significantly reduced the ULA, when compared to the saline group (75 ± 8,6).
According to the results for the somatostatin model, we observe that the Sa-FRF (77 ± 17*), the Sb-FRF (82 ± 8,2*), and lanzoprazole (88 ± 22*) significantly increased serum somatostatin levels when compared with the saline group (20 ± 7,5).
It is seen that the SD-FRF has a similar format to the conventional receptance FRF.
