Sentence examples for Target-focused from inspiring English sources

Gamma-secretase inhibitors developed at Eli Lilly and Company (Indianapolis, IN, USA) and Bristol-Myers Squibb CompaNJ (Princeton, NJ, USA) (semagacestat and BMS-708163, respectively) showed good target-focused preclinical animal data, reducing Aβ levels in mice and in the spinal fluid of human patients in a phase 2 study [ 4, 5].

Target-focused libraries are either designed or assembled upon some understanding of a specific protein target or a protein family.

Target-focused libraries are often constructed around a single scaffold with one or more positions used to attach various chemical moieties or side chains.

In recent years, the focus has shifted away from screening large compound libraries to screening smaller, more target-focused libraries that are generated using all relevant information about the target and its known active compounds [13 17].

But when it comes to investing in employment support, Di Lella believes the government is looking to make short-term savings by favouring cheaper, generic, target-focused services.

For the majority of target-focused drug discovery projects the application of protein crystallography as one key technology today is a routine process.

The FBI – which doubled the reward for the arrest of Bulger to $2m£1.3m3m) last year, the largest ever for a domestic target – focused on women in their sixties.

The optimization target focused on maximizing efficiency, while keeping NOx emissions, peak pressure and maximum pressure rise rate under the baseline engine levels.

The goal, he says, is to "target focused sound so that a person can walk around an office and hear" while on a video- or computer-aided audio conference call.

Together with targets focusing on poverty, health, hunger and education, environmental targets are on the shortlist.

PETA has turned Ringling Brothers into one of its main targets, focusing on the care of elephants.