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T-box brain 1 transcription factor.
T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development.
T-box TFs can bind to dimeric sites, with the characteristic spacing and orientation varying among different T-box proteins (Jolma et al., 2013).
T-box genes mutations in humans are associated with CHD [ 9– 11].
T-box containing transcription factors regulate many aspects of mesoderm fate including segmentation and somite patterning.
T-box domains were more abundant in coral than other species.
The vertebrate T-box transcription factor gene Tbx18 performs a vital role in development of multiple organ systems.
Western blotting demonstrates low expression levels of connexin 43 and T-box 3 proteins in P2KO compared to wildtype (WT).
TBR1 is also known as T-box Brain Protein, T-Brain 1, and TES-56.
Furthermore, twelve of the sRNAs contain a putative T-box, and a tandem T-box was found upstream SA1199.
The T-box (Tbx) family of transcription factors is represented in all metazoans [1] and is characterized by a highly conserved DNA binding domain, the T-box domain.
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