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"We're looking into the matter to see if we can substantiate if there was a violation of the standard of care," a board spokeswoman said.
Additional control experiments and further discussion of the literature as suggested below are required to substantiate if the proposed mechanism indeed holds true. 1) One concern is the quantification of all the various phenomenon described in this work.
To substantiate if increased cAMP signalling facilitates a growth advantage in the AI phenotype, we then stimulated PC3 cells with the adenylyl cyclase activator, forskolin (10 μ M) and observed a marked increase in proliferation rate, which was insensitive to treatment with the PDE4 inhibitor rolipram (10 μ M; Supplementary Figure 3).
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The PCC's director, Stephen Abell, is clearly aware of the implications, seeing it as "a significant ruling" and arguing: "There is plenty of room for robust opinions, views and commentary but statements of fact must still be substantiated if and when they are disputed.
I feel that fear is substantiated, if you think about the fact that housing is something so important to us.
This hypothesis would be further substantiated if the correlation is with active cellular crescents accompanied by necrosis rather than with fibrotic crescents accompanied by glomerular scarring.
This notion could be substantiated if an independent relationship could be established between arterial stiffness and cardiac function in type 1 DM.
It is up to taxpayers to claim their deductions and be able to substantiate them, if asked.
While I don't have numbers to substantiate this, if you are an Instragram user, there is no way you haven't noticed a clear uptick of businesses posting photos with the intent to increase clientele.
C. Lee Peeler, president and chief executive of the National Advertising Review Council, says his advisory group applies the same standards to advertising as does the Federal Trade Commission: They ask if ad claims are substantiated and if anything in the ad is misleading.
While Williams' allegations have not been substantiated, even if they are later proven, his actions certainly cannot be condoned.
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