Substantial strides have been made in advancing our understanding of the pathogenesis of these diseases (for reviews, see Xavier and Podolsky, 2007; Afrazi et al., 2010), but many fundamental questions still remain largely unanswered, which has left a large gap between the therapies that we have and the therapies that our patients need.
Together we can make substantial strides forward.
"I think we've made substantial strides".
Despite the obstacles, Greece has made substantial strides.
Galpin is hoping to influence similar changes in Afghanistan, where female athletes have made substantial strides.
House Republicans have made substantial strides in the South in recent years, gains that are crucial to the Republican Party's goal of becoming the majority party.
The New York City Housing Authority said on Monday that it had made substantial strides in catching up on repairs at its buildings, fulfilling 73,000 work orders since January.
In our report we looked at their subsequent experience, which was mixed, but also at five states that had made substantial strides in health outcomes in the years since then.
Through a unified organisation, London & Partners, it has delivered a consistent message to the world that it is open for business and investment and has made substantial strides in becoming a city that welcomes new technology and science industries.
"Despite promising improvement in select areas, the health care system is not achieving the more substantial strides needed to close the gap or 'quality chasm' that persists," the report concluded.
"Despite promising improvements in a few areas of health care," Dr. Clancy said, "we are not achieving the more substantial strides that are needed to address persistent gaps in quality and access".
