In Drosophila, where the morphology of LNs has been studied systematically (Chou et al., 2010), most LNs branch across all glomeruli, but a substantial part omits some glomeruli, or has a patchy innervation pattern.
Put another way, there needs to be a substantial likelihood that the omitted information would have been viewed by the reasonable investor as having significantly altered the total mix of available information.
STATE COUNSELLOR OF JUSTICE M. Y. RAGINSKY (Assistant Prosecutor for the U.S.S.R .: Defendant Speer, when you told your biography to the Tribunal and answered the questions of Justice Jackson, I think you omitted some substantial matters.
As discussed below, materiality requires a substantial likelihood that the omitted information will be viewed by the reasonable investor as having significantly altered the total mix of available information.
The cut-off value has been selected so that, for patients with a low probability of invasion, an axillary procedure can be omitted without substantial risk of their needing to undergo additional surgery, while patients with a high probability of invasion can be offered up-front SLNB.
…There is a substantial and material question of fact as to whether Sinclair affirmatively misrepresented or omitted material facts with the intent to consummate this transaction without fully complying with our broadcast ownership rules.
Second, when circumstances are shown such as those which induced these declarations, it is immaterial whether the declarations be termed 'exculpatory.' 13 Thus we find no substantial reason to omit Toy's declarations from the protection of the exclusionary rule.
Last October, when it was floated with a £3.3bn price tag, property experts pointed out that the valuation of Royal Mail omitted the three substantial development sites it owns in London, which were themselves valued at £1 - £1.5bn.
Patient 10 was omitted because of substantial independent bone marker migrations (ME > 0.2 mm).
In patients with a low probability of invasion, an axillary procedure can be omitted without a substantial risk of additional surgery.
