Sentence examples for Suboptimal functioning from inspiring English sources

Therefore, it could be postulated that a suboptimal functioning of the gain control in the light-governed entrainment system could induce dysfunctional hypothalamic homeostatic mechanisms [3], leading in turn to increased attack propensity.

At the macro level, dystechnia is a condition of suboptimal functioning in the socio-technologic-economic network, where the yield from resources and the efficacy of transactional logistics is compromised by latent demand for technological innovation (EG Carayannis and MR Stewart,2007 2011, unpublished lecture notes; Stewart2011; Stewart and Carayannis2011).

Like neurocognitive deficits, many of these social cognitive problems are thought to be stable across phases of illness and linked to suboptimal functioning [ 17, 27].

Neuroplastic changes in response to alcohol or other addictive substances are most commonly regarded as negative neuroplasticity associated with suboptimal functioning and maladaptive behaviors (Kalivas and O'Brien 2008).

For instance, to date no instruments exist to measure the high burden that BPD patients can impose upon colleagues and organizations due to suboptimal functioning at work [ 72].

However, the tissue-specific nature of LCRs and their general large size places significant restrictions on their utility, which has resulted in suboptimal functioning and only partial negation of insertion-site position effects.

Current treatment options often result in suboptimal functions that lead to patient morbidity and diminished quality of life.

Good function of the knee depends not only on stability and a good range of painless motion but also on the absence of residual deformities or muscle weakness which may lead suboptimal function.

Thus, the presence of more immature DCs with suboptimal function would provide even more targets to support HIV replication in the absence of maximal immune activity.

It is tempting to speculate that due to such suboptimal function, Jβ RSS sequences may have been selected in order to maintain the B12/23 constraint (i.e., avoid PC nucleation at Jβ RSSs).

In some cases having suboptimal function in only one or two of the genes may have been sufficient to permit interferon α-based therapy to drive the HCV to extinction.