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In a report released Friday, the Institute of Medicine, the nation's leading medical advisory group, seemed to side with those who have argued that observational studies are adequate.
Indirect comparisons may then be used to determine the relative effectiveness, provided studies are adequate for indirect comparisons (§ 5 par. 5 AM-NutzenV).
Previous studies have reported a strong correlation between sstr mRNA and protein expression, suggesting that transcriptional studies are adequate for profiling this receptor family (Kumar et al. 2005; Wang et al. 2008; Schaer et al. 1997).
I don't think it will take very long to conduct the studies themselves, because ultimately the Commission staff has to determine whether they feel the studies are adequate.
Under rare-variant with medium- to high-penetrance models (odds-ratios between 1.6 and 4.0), studies comparable in size to many existing studies are adequate provided the genotyping technology can interrogate more and rarer variants.
Apart from two exceptions, physical examination and imaging studies are adequate for establishing regional lymph node involvement, precluding the need for routine surgical sampling of 'benign' nodes.
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In October, the Bank of England acknowledged that none of the published studies was adequate, but for the Conservatives they all pose the same problem: how to maintain the openness and dynamism of the UK economy in the face of a Brexit.
Overall, the reporting quality of the studies was adequate.
The methodological quality of the selected studies was adequate to high.
Dosing regimens in the four animal feeding studies were adequate to detect cancer based on range-finding studies.
This topic has been discussed in the literature and combining both types of studies was adequate for our aim [ 3].
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CEO of Professional Science Editing for Scientists @ prosciediting.com