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Structural requirement of the sterol side chain for the silkworm growth and development.
Structural requirement for proteasome recognition and degradation in the absence of ubiquitin have been thoroughly studied for thymidylate synthase, apomyoglobin and p53 [ 42– 42].
To identify the structural requirement for development of lead structures with PPAR gamma binding activity group based quantitative structure activity relationship (GQSAR) studies on 46 reported structures were carried out.
A cis-diol motif may thus be a structural requirement, and if encountered in a ring system, it may be required that the two -OH groups be vicinal and syn-oriented.
Studies using a number of structurally related thiols (mono-, di- and trithiols) showed that the major structural requirement for in vivo chelation of Cd from intracellular MT were the vicinal thiol groups on an aliphatic chain, and lipophilicity.
For the structural requirement, the material should be non magnetic.
Furthermore, analysis of the contour maps helped to provide guidelines for finding structural requirement.
As design constraints, both the manufacturing process requirement and the structural requirement were considered.
To clarify the structural requirement for inhibition, some structure activity relationships were determined.
A set of nesC programme was designed to review the structural requirement.
As a structural requirement, either the stiffness constraint or strength constraint was selected.
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