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Several procedural and statistical precautions were taken to reduce error in comparing multiple samples.
However, there is no logical reason why these differences should cause a specific SNP distribution to change, especially when the standard statistical precautions of measuring HWE and LD on other available SNP data are observed.
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The statistical agencies take many precautions to inspire confidence in government data.
Lessons have been learned about the statistical and study design precautions needed when applying such strategies of measuring large numbers of molecular components [ 20, 21].
Note that also in the second experiment (using the "public participation" as the precautionary measure), the results are in the same direction: Under the "precaution" condition, the mean ratings for "feeling threatened" were higher than under the "no precaution" condition however, the difference did not reach statistical significance.
As a precaution against the risk of Type I errors, the statistical plan prioritised testing of the primary hypotheses of interest (differences at baseline and time of maximum clinical effect i.e. week 6).
Yet, although statistical significance was found in these results, exploratory analysis of linear measurements with high heterogeneity imposes precautions in the validity of these results.
Here we had to take some additional precautions due to the clustering of offenders by case, which risked violating the assumption of independence underpinning most inferential statistical tests (Kreft and de Leeuw 1998).
Except in the statistical sense, it can't be proved whether the thing you sought to prevent -- be it cancer, cavities or a catastrophic tree accident -- would have ever happened if you hadn't taken precautions.
"You take precautions".
Precautions are under way.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com