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12 15–17 Several threats to validity have been identified, including inadequate sample sizes, data-driven or arbitrary categorisation of continuous predictors, inadequate statistical modelling of non-linear relationships, inappropriate handling of missing data, and failure to check model assumptions.

In this section, we sketch the design of a general model of linear relationships.

Statistical Modeling of RNA-Seq Data.

Model results were evaluated based on the following statistical indices: (a) Pearson's correlation coefficient r that describes the degree of linear relationship between forecasted and real (hbox {PM}_{10}) concentration values.

Lectures will cover basic elements of statistical modeling (generalized linear models, likelihood and Bayesian analysis, conditional probability, latent or unobserved states).

Second, they produce models capturing non-linear relationships in the data, instead of simply modeling only linear relationships, like traditional linear regression models often used in QSPkR studies.

All model assumptions, including normality, equal variance of residuals, model fitness, linear relationships, and absence of statistical interaction were tested and met.

The non-linear receiver needs the knowledge of a statistical model of the noise.

Only two models (Eqs. (3) and (4)) comply with the requirement on statistical significance of a linear relationship based on the results of an F-test (Table 1).

The statistical maximum likelihood model used to generate these estimated effects assumes multivariate normality of the model residuals, linear relationships, and homoscedasticity.

Logistic regression uses a statistical model that assumes a linear relationship among attributes[ 55].

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