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Transition of new DNA sequencing methodologies to the clinical laboratory is under way and is likely to have a major impact on all areas of medicine.
Advances in modern DNA sequencing methodologies now make it possible to answer these questions with greater certainty.
Since Dr. Wu first developed the DNA sequencing methodology, and established the primer-extension principle, "father of DNA sequencing" should be a correct title for him.
Both tests employ DNA sequencing methodology and are approved and validated; most tests were performed with TRUGENE Kit®.
However, advances in contemporary DNA-sequencing methodology make gene-based diagnosis increasingly feasible in routine clinical practice.
Therefore, the proposed sophisticated DNA strand displacement-based methodology with engineering dynamic functions may find broad applications in the construction of programming DNA nanostructures, amplification biosensing platform, and large-scale DNA circuits.
The new species were discovered by using a combination of sophisticated molecular analyses, including DNA sequencing; digital imaging, such as X-ray computed tomography; and statistical analysis of external and internal anatomy.
The ease of DNA sequencing has revolutionized phylogenetic methodology.
Fifth, early cancer gene DNA sequencing studies using Sanger methodology revealed mutation patterns biased to cytosine bases [ 32- 34].
Thus even a wide range of mutation detection methodologies exist, DNA sequencing technology has been considered as the gold standard.
With the rapid development of DNA microarray technology and next-generation sequencing methodologies, analysis of the transcriptome is now commonplace.
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