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Church argues in his Nature editorial that "replacing deleterious mutations with common variants is unlikely to lead to unforeseen effects and is probably reversible". But what about effects we can somewhat foresee but aren't necessarily universally viewed as desirable?
It can be foreseen that the drugs will shorten life somewhat but the purpose of the action is to reduce pain.
All this was foreseen by Keynes in his General Theory: "I am now somewhat sceptical of the success of a merely monetary policy directed towards influencing the rate of interest.
The islands were shrouded in ominous-looking mists, and the Pacific had been rough all day, but Graham had foreseen that the waters in the islands' lee might be somewhat calmer, and over the next couple of hours the Phantom trials proceeded as we lay anchored there.
IN THE final chapter of his "General Theory", Keynes foresaw "a somewhat comprehensive socialisation of investment".
The ratio of twice as many short puts suggests that, while the trader expects the price of the underlying to pull back somewhat, he does not foresee an all out collapse in the ETFs share price in the near future.
So far, so foreseen.
He had foreseen her suicide.
He had foreseen.
Such reaction was foreseen.
You couldn't have foreseen.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com