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Some databases, though, provide scant details of the reason for the negative mark, according to a review of more two dozen letters.
Some databases address specific research interests.
Some databases are not updated regularly or instead frequently revised.
Some databases had pre-set search dates dependent on the search term entered.
Some databases are general purpose; others are focused on a specific area of research, such as drugs and their targets or metabolites found in the human body.
Some databases such as the Kyoto Encyclopedia for Genes and Genomes and RMG do not report an atom atom mapping (AAM) for the reactions.
Some databases used for this purpose lack reference profiles for Brucella species, which is still an important pathogen in wide areas around the world.
Some databases address such problems by implementing methodological shortcuts.
Some databases were established as early as the 1920s.
Some databases have had substantial investment in their IT infrastructure.
Some databases have already started to provide user feedback systems into their interfaces (31, 32).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com