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So trial lawyers are attempting not only to catch up, but to be a copy cat.
"Libyans have no experience in ruling themselves, so trial and error is to be expected," Tekbali observes.
Trial investigators will be crafty in any potential efforts to decipher the allocation sequence, so trial designers must be just as clever in their design efforts to prevent deciphering.
This "I'm going to take my toys and go home" attitude is injurious to our needs as a country -- we need to fill these vacancies so trial can be held, opinions written, and decisions made both on the bench and before it.
43 NA=outcome was prevention of death so trial cannot be interpreted in terms of improvement.
We expect β1 jk to be negative, so trial results yielding larger standard errors have lower propensity to be published.
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This is new territory, so trial-and-error and learning from others is key.
Research is going on into ways to make new vaccines quickly, so trials can start within days of an outbreak.
Like all other drugs, there is a lack of clinical evidence about whether it does work and stocks have been extremely limited so trials have been hampered.
Plasma is given routinely to patients, so trials of this approach, unlike those testing a new protein, would not require U.S. Food and Drug Administration approval, Wyss-Coray says.
That's because the trial stage is supposed to last three months, so trials begun after that date are not expected to have a final outcome.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com