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So, activate the system!
These proteins, collectively called acute-phase proteins, bind to bacteria and, by doing so, activate complement proteins that destroy the pathogen.
This universal triad of stress effects was seen repeatedly after any noxious or aversive event (i.e., noise, shock, etc).. "Any activity, any emotion, from crossing a busy street to exposure to drafts, or even sheer joy, is enough to set the adrenal glands spurting and so activate the body's stress mechanism".
Once activated by DAMPs the receptors form oligomers with inflammatory caspases (CASP1/5) and in doing so activate the cleavage of the caspases [ 49].
The upstream steps in the stress-induced modification of PTP3 are also largely unknown, although pharmacological agents that increase cytosolic calcium levels stimulate phosphorylation of PTP3 and so activate STATc (Araki et al., 2010).
It could be argued that the many pharmacological agents known to induce preconditioning, from KATP channel openers, to uncouplers and respiratory chain inhibitors (see Section 10), might all represent insults to the heart that increase AMP and so activate AMPK as the focus of a common signalling mechanism to protect the heart [133].
Similar(52)
After being so activated by the addition of a phosphate, Sae2 uses its endonuclease activity to make a clean cut near a double-strand break in DNA.
If so, activated RAC1 could therefore favor the response of LNCaP cells to the mitogenic activity of IL-6 and CCL5 meanwhile participating to the induction of their expression.
I am hoping my cells get so activated that someone will card me, if only to deny me a senior discount at the movies.
It involves antibodies on a surface reacting with the molecule being tested for, and so activating a dye.
"I said, 'Slam it on your desk.' " Doing so activated a sound chip inside the 5-inch pillow on which the noise of a cocktail party had been recorded.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com