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The phrase "Since its conception" is a correct and usable phrase in written English
You can use it when talking about something that was created at some point in the past. For example: "Since its conception in 1957, the company has grown significantly."
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SINCE its conception nearly a decade ago, the Dabhol power project in the Indian state of Maharashtra has generated more problems than power.
Since its conception, many public and private planning agencies and organizations have endorsed this concept (Arku, 2009).
Since its conception, the institute has traveled to Athens, Kiev and São Paulo.
Since its conception, the Bronx Borough Courthouse has been a symbol of the borough's struggle for its own identity.
Since its conception nearly two decades ago, cognitive load theory (CLT) has been a fertile ground for both empirical and theoretical investigations.
Since its conception in the 1950's, the highway fund has helped to build 42,800 miles of Interstate roads, at cost of $108 billion.
Since its conception, Siren has had a few versions of its socks.
Since its conception in 2010 and launch in January 2011, Kallery tells Forbes Lifecom that membership has grown to 10,000.com
Since its conception in the mid 1970s, the boombox portable cassette player has become a symbol for urban communities, youth culture, and the unifying power of music.
Since its conception as a water pumping station in 1883, Muffathalle has since been redesigned into an urban-chic music venue.
Since its conception in 2013, the parties have featured an impressive lineup of Canadian female producers including Bambii and Debbie Doe.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com