Sentence examples for Since constitutive from inspiring English sources
Since constitutive signaling is important for normal GPCR function and altered basal activity can result in pathological disease states [37], [38], high-basal and low-basal RASSL variants could have specific applications for the study of the physiological role of constitutive signaling in vivo.
Since constitutive activation of nuclear factor-κB (NF-κB) is necessary for tumour progression, NF-κB may be an important pharmacological target for this disease.
Since constitutive expression of TrAP reduced H3K9me2 in vivo, we wondered if Geminivirus infection could also decrease the repressive marks in the host.
Since constitutive activation of GNA3 in T. reesei is suggested to positively influence mycoparasitism, a similar mechanism, may be at work in this fungus (Silva et al. 2009).
Since constitutive activation of the WNT pathway by lithium sensitizes TP53 mutant medulloblastoma cells and protect normal neural stem cells from radiation, this oral drug may represent an attractive novel therapy for high-risk medulloblastomas.
Since constitutive Nanog expression is likely to interfere with embryonic development, we opted to assess developmental potential 52 hr after morula aggregation, which corresponds to a late blastocyst stage.
The classical plasticity theories cannot explain this size effect since their constitutive laws possess no internal material lengths.
This size effect cannot be explained by classical plasticity theories since their constitutive relations do not have an intrinsic material length.
Since the constitutive equation is a non-linear differential equation, the axial and tangential/spanwise flows are coupled in a complex way.
Since the constitutive laws for orthotropic materials are complex, simplifications in the general form of the strain-energy function are often made for mathematical tractability, the most common being strain energies that depend only on the I1, I4, I6 invariants.
Transgenic approaches identified SUB1A-1 as the major tolerance gene, since its constitutive expression conferred submergence tolerance to an intolerant rice variety (M202), which naturally lacks the SUB1A gene (Xu et al., 2006).
