Since completion of those controlled trials, further studies have been completed (n = 2) or are ongoing (n = 3), in which an additional 1846 patients have received drotrecogin alfa (activated).
Since completion, the business has generated $8 billion of cash, after capital expenditure and license costs but before tax, according to one analyst's estimates.
Since completion of the 1944 lava dome, geophysical explorations and deformation analyses of the lava dome have been carried out, but without any convincing results.
Since completion of the freeway, the route has not been changed.
Since completion, PA 378 has undergone little major change, but the highway has undergone several rehabilitations.
Since completion of construction, the road has retained its original designation from I-25 to I-70.
Since completion in 2005, it has reduced carbon dioxide emissions from city traffic by an impressive 47,000 tons a year, and has drastically reduced commute times.
Since completion as a four-lane route, expansion work has been concentrated on the portion of the freeway in Sarnia approaching the border crossing.
Since completion, the freeway has been upgraded with the construction of the Zilwaukee Bridge near Saginaw and improved connections to the Ambassador Bridge in Detroit.
Since completion, the parkway has not been changed significantly, other than adding one partial interchange at Wynford Drive and updating its infrastructure to current standards.
Since completion of this clinical trial, Tasanh has been at the center of a high profile containment program; only time will tell if these efforts have been successful or whether artemisinin resistant clones have already spread.
