In our previous work, a nanostructured SU-8 substrate exhibited similar neuronal outgrowth to a flat SU-8 surface coated with poly-l-lysine (PLL), which facilitates adhesion by rat pheochromocytoma (PC12) cells [17, 18].
e Quantification of the percent of neurite bearing cells shows similar neurite outgrowth for cells either not exposed or exposed to magnetic nanospheres at iron concentrations of 0.34 and 6.0 mM and treated with NGF, all of which increased neurite outgrowth compared to cells not treated with NGF.
We show similar axon outgrowth defects also occur in mutants in which the C. elegans beta-tubulin TBB-2 is deleted.
Although null mutations of tba-1 show a nearly wild-type pattern, similar axon outgrowth defects were observed in animals lacking the beta-tubulin TBB-2.
Cultures treated with OLFM1 displayed a similar endothelial outgrowth and a greater number of mesenchymal cells (Fig. 3B,F).
The OTX2-hESC grafts exhibited a similar axonal outgrowth pattern to the WT hESCs, with large numbers of hNCAM+ axons extending rostral within the MFB.
A search in rpk1-6 for a similar ectopic outgrowth revealed not more than one case among 737 seedlings (Fig. 2g) showing that this special structure is significantly rare.
In vitro, naïve GSK3βSer9Ala KI DRG neurons displayed a similar neurite outgrowth to that of naïve WT neurons and the percentage of longer neurites was increased following conditioning lesion.
