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As a group it has a significantly atypical nucleotide composition (P<0.0001) relative to the genome and the gene content (1497 CDSs) that is more highly conserved with the genus (Figure S1).
The start of the large aromatic island was defined by a region of significantly atypical composition.
In this study we have identified a new cohort of patients with dopamine transporter deficiency syndrome, including, most significantly, atypical presentation later in childhood with a milder disease course.
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In yeast, deleting the nap1 gene significantly increases atypical histone DNA complexes [ 26].
However, there was significantly more atypical EPEC detected in non-diarrheal controls than in diarrheal cases (50% versus 18%; P < 0.001, χ test).
In fact, in BED patients they have been evidenced significantly more atypical eating behaviors, like dietary restraint or morning under-eating, or recurrent overeating patterns like eating double meals, or nocturnal eating and snack consumption [ 18, 32].
In 118 children and adults attending three European epilepsy clinics, we used an objective measure called Face Shape Difference to show that those with pathogenic structural variants have a significantly more atypical face shape than those without such variants.
Combined data for the Netherlands and Vietnam showed significantly more atypical Beijing isolates among patients >75 years of age (odds ratio [OR] 2.96, 95% confidence interval [CI] 1.15 7.67) (Table 1), which suggests more recent introduction and spread of typical Beijing strains.
Both paa and lpfA were found to be significantly associated with atypical EPEC diarrhoeal isolates in a microarray study of pathogenesis related genes [48].
Moreover, PPI deficit observed in HB-EGF KO mice were significantly reversed by atypical antipsychotics, risperidone and clozapine (P<0.05 vs. vehicle-treated HB-EGF KO mice), but not by a typical neuroleptic haloperidol (P>0.05).
Other inhibitory receptors significantly upregulated by atypical MBCs included CD72, CD200R1, LILRB1, LILRB2 and FCGR2B.
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