If the court were to rule the law unconstitutional when it issues its decision in June, it could prove a significant blow to Obama's re-election campaign by striking down his most important piece of legislation and bolstering conservative opposition.
Similarly, Marshall told me there is a significant lack of advice available to disabled aspiring journalists.
A significant thread in the recent politics of Tower Hamlets is the legacy of the Battle of Cable Street, the legendary East End street confrontation involving the police, local Jewish and Irish workers and activists, and Sir Oswald Mosley's British Union of Fascists that took place on 4 October, 1936.
The US Senate on Tuesday passed a bill to end the bulk collection of millions of Americans' phone records, ushering in the country's most significant surveillance reform since 1978 two years after NSA whistleblower Edward Snowden's revelations to the Guardian.
In potentially the most significant announcement, Ed Davey, the energy secretary, said he expected to start talks next month with Tidal Lagoon Power, the company that is aiming to build the world's first tidal lagoon power plant in Swansea Bay, to see if the project is affordable and value for money for consumers.
Tributes have been pouring in from across the political spectrum with Tony Abbott describing Wran as one of the most significant figures of his generation.
Victoria Jaye, head of TV content for the BBC iPlayer, said on a BBC blog there had been a "significant surge in BBC iPlayer usage, as people all over the country un-wrap new devices and take the opportunity to enjoy our terrific range of programmes, at a time that suits them".
"My sense of unease, my concern about what was going on within Eric Roozendaal's office to do with Buildev, and Nathan Tinkler, was significant".
This led to significant snarking online: "Look he didn't molest ALL of us – some of us he cast in movies!" tweeted writer Sady Doyle, referring to allegations that Allen molested his daughter.
The first leg of the Uefa Cup final would see also see Thomson play a significant role.
"After many fantastic years with the BBC, I'm delighted to be helping to lead the ITV team responsible not just for breaking some of the UK's most significant stories - notably the Jimmy Savile scandal - but also for making the most consistently popular Current Affairs TV programming in the UK," said Giles.
