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Certainly, Camp David represents a significant juncture in the history of the Israeli-Palestinian conflict.
"I don't see it that way," replies McCoist when asked if this marked a significant juncture in his career.
Even at such a significant juncture in his own life, Wicks paused to ask himself what parliament had to offer such a citizen.
This story is not just being played out north of the border: UK-wide polling shows the Tories and Labour scoring some of their lowest-ever combined shares of the vote, the inconclusive result of the last general election suggested a very significant juncture had been reached – and the fact that next year's result is anyone's guess only underlines the point.
High-profile court cases like the one in question have a history of dragging through many adjournments and that will leave a cloud over Liverpool's captain at arguably the most significant juncture in his footballing life, with the drive towards the Premier League title Anfield is obsessed about finally a reality.
Given that the venture capital (and startup) landscape in Israel is at a potentially significant juncture — the most recent exit being Waze to Google for $1.1 billion — the founders want to strike while the iron is hot.
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He pops up at other significant junctures, too.
But on other issues, he has seemed uninvolved at significant junctures.
I'm halfway through life now and I can see that of the significant junctures that brought me here – such as meeting my [second] husband while hunting through the classified ads sections of The Lady and getting a job as a receptionist at [clothes shop] Thomas Pink [where they met] – all came about by chance; not one thing was carefully planned.
We are approaching as significant a juncture in the fate of the Scotland national team as we have in years.
Mr Kerry said the recent upsurge in fighting was "an alarming situation" adding that the US was "particularly concerned" by rebel moves to "attempt to gain control of a very significant rail juncture" in eastern Ukraine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com