Restricting the global tree t to a per-gene subtree for the available molecular data, therefore, allows to save both, a significant amount of floating point operations as well as a significant amount of memory space for storing ancestral probability vectors.
Main effects and interaction terms of the formulation variables were evaluated quantitatively using a mathematical model approach showing that both independent variables have significant effects on floating lag time, % drug release at 1 h (D1 h) and time required to release 90% of the drug (t90).
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Whereas Dyrk1A+/− mice did not show significant amounts of floating in any of the testing periods, wild types showed a significantly higher percentage and time of floating behaviors that was decreased along acquisition sessions, but increased again in the visible platform and reversal learning sessions (Fig. 2A and 2B).
These transfectants also produced a significant number of floating cells, which suggested that a fraction of the transfectants continuously died.
In these studies, we found that the concentration of sodium alginate and HPMC had significant influence on floating lag time, gelling capacity, and cumulative percentage drug release.
They already demonstrated a significant production of floating cells 5 days after the addition of CSM and a sufficient number of spheres for subsequent experiments were obtained after 3 4 weeks.
Furthermore, cell culture of these clones was always accompanied by a significant number of floating cells that could be stained readily with trypan blue, even after replacing with fresh medium.
In an office near the State Capitol, Mr. Lasher and eight staff members scrutinize every significant piece of paper floating through the Legislature.
Although the analysis of the number of floating episodes (Fig. 2A) or the cumulative floating time (Fig. 2B) did not reveal a significant effect of genotype on floating behavior for the acquisition, visible, probe and reverse platform tasks (t = 0.130, P = 0.898, Student's t test), a clear difference in the floating pattern along sessions was observed between Dyrk1A+/− and wild type mice.
