Sentence examples for Serious obstacle from inspiring English sources

The Canadian Shield posed a serious obstacle to transcontinental planning.

The most serious obstacle is Israeli and ideological.

The most serious obstacle is the severe economic constraints on defense resources.

Another serious obstacle was the cumbersome federal structure inherited from the communists.

Usability problems associated with virtual environments are a serious obstacle to their successful development.

Resistance to antineoplastic drugs represents a serious obstacle to successful cancer treatment.

This is a serious obstacle in applications such as law enforcement and surveillance systems.

A serious obstacle to China's economic reform is the lack of a sustainable pension system.

The local character of this meteorological phenomenon is a serious obstacle to forecasting.

Nonetheless, the lack of experimental data regarding this option is a serious obstacle.

And you never see him, as one saw Laughton, as a serious obstacle to Maggie's success.