Sentence examples for Selective phenotyping from inspiring English sources

Within each litter, pigs were selected for transcriptional profiling using a selective phenotyping strategy which consisted of choosing the two extreme males and females within each litter for a trait of interest.

This will in turn enable scientists to work with substantially larger effective population sizes for mapping complex agronomic traits using selective phenotyping approaches [15].

SlanDCs are a major population of proinflammatory human blood DCs, which mainly differ from other blood DC subsets by their selective phenotype (6-sulfo LacNAc+ ( =  slan+), CD1c−, CD11c+, CD14−, CD16+, CD45RA+, C5aR+) [11] [12], [12].

We then applied both BSA and ISA to dissect another selective phenotype, high-temperature growth.

We identified zonation-related expression profiles contributing to selective phenotypes of HCC, by integrating relevant experimental observations through gene set enrichment analysis (GSEA).

To begin to address the basis of the cytarabine selectivity, we performed cell viability assays to assess whether other cytosine-based nucleoside analogues might exhibit the same MLH1-deficient selective phenotype.

The low MAF but relatively high LD illustrates a yin and yang of LD mapping of strongly-selected phenotypes: selective sweeps reduce local MAFs (and power) and increase LD (and power).

Finally, synthetic modifications made to the small molecule resulted in the identification of the structural components that contribute to C-6's cancer-selective phenotype.

Collectively, the structural studies indicate that while C-6's potency can tolerate a variety of functional group modifications, the cancer-selective phenotype is especially sensitive to these alterations.

However, conversion of C-6's carbamate ester to an aryl sulfonamide resulted in a complete loss of selectivity (analogs 2 and 3); replacing the tert-butyl group of the carbamate with a methyl group also attenuated the cancer-selective phenotype but to a lesser degree (analog 4).

Together these data demonstrate that C-6 causes a selective cytostatic phenotype in breast cancer cell lines.