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Our in vitro assays confirmed the expression, release and selective killing effect of the immunotoxin produced by hMSCs.
Selective killing of cancer cells is one of the major goals of cancer therapy.
Selective killing of AspM/Nestin+ cells was obtained by treating mice with Gancyclovir (GCV) from E14.5 until E18.5.
Selective killing of cancer cells, a property of several known ROS-enhancing small molecules, was modest and limited to several electrophilic small molecules.
Highly selective killing of Pten-null cells can be achieved by deguelin, a natural insecticide.
These findings suggest that selective killing of virus-producing cells might represent a novel therapeutic strategy.
Therefore, unlike chemotherapeutic agents, these receptors can potentially mediate selective killing of tumor cells.
And TOPFNs have a selective killing ability for MRSA with minimum damage to L-929 cells.
Pentobra demonstrated potent and selective killing of P. acnes but not against human skin cells in vitro.
Cisplatin, an anticancer drug has been commercially developed for selective killing of cancerous cells without any effect on non-cancerous or normal cells.
Such selective killing of leukemic cells can also be achieved by inhibiting cyclin D associated kinase activity in mouse and human T-ALL models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com