Sentence examples for Selective deletion from inspiring English sources

Selective deletion of the ERα gene in mouse prostate epithelial cells by probasin-Cre does not affect the regular prostate development and homeostasis.

Selective deletion of the DG gene in brain leads to defects in morphogenesis, including malformation of cortical lamina and neuronal migration errors similar to mutations that affect glycosylation and ligand binding of α-DG [6], [7].

Selective deletion of the phosphatase and tensin homologue, PTEN, an antagonist of PI3K signaling, in β cells results in a 4.5-fold increase in total islet area by increasing both cell size and number [22], [23].

Selective deletion of the PR isoform showed distinct functions in vivo [ 74, 75].

Selective deletion of TRPM4 from the heart muscle in mice resulted in an increased hypertrophic growth after chronic angiotensin (AngII) treatment, compared to WT mice.

Selective deletion of TCF7L2 in mouse pancreas impairs insulin release and glucose homeostasis, indicating the direct role of this factor in controlling β-cell function.

Selective deletion of MARCKS in ependyma results in precocious emergence of biomarkers for aging, both in ECs and in the brain interstitium.

Selective deletion of IR in midbrain (including VTA and substantia nigra) TH (tyrosine hydroxylase) -expressing neurons could abolish insulin-mediated increase of firing rate in TH-positive neurons [ 100].

Selective deletion of the adenomatous polyposis coli (APC) gene in Lgr5+ cells demonstrated that aberrant activation of Wnt signalling in these cells causes aggressive adenoma growth throughout the intestine.

In addition, the selective deletion of protein phosphatase PP2B selectively abolished postsynaptic PF-PC LTP [22].

Shi, S. et al. Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.